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Understanding Chronic Inflammatory Response Syndrome

CIRS: Symptoms, Causes & Nervous System Dysregulation

Chronic Inflammatory Response Syndrome (CIRS) describes a pattern in which the body develops a persistent inflammatory response following exposure to environmental biotoxins, most commonly associated with water-damaged buildings. These environments can release mold fragments, microbial byproducts, and other contaminants that may act as ongoing stressors to the immune and nervous systems. Individuals may experience symptoms such as fatigue, cognitive fog, headaches, dizziness, respiratory irritation, muscle or joint discomfort, and difficulty tolerating environmental exposures.

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While these symptoms can be distressing, they do not necessarily indicate permanent damage. Rather, they often reflect regulatory systems that remain activated after significant environmental stress. Identifying and addressing environmental exposures is therefore an important step in restoring stability. With appropriate attention to environmental conditions, along with strategies that support nervous system regulation and physiologic recovery, many individuals see symptoms gradually improve as the body moves toward a more stable baseline.

Abstract Tree with Branches

Our Approach to CIRS

Our work focuses on identifying environmental factors and response patterns that may be influencing symptoms in individuals experiencing CIRS and related conditions. This includes evaluating possible exposure to water-damaged buildings, mold-related contaminants, and other environmental stressors.

When environmental concerns are present, we review available environmental information and help identify practical steps to reduce or correct those triggers.

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Our approach does not emphasize detox protocols. The body already has natural detoxification systems, and the priority is addressing the environmental source of exposure.

If symptoms persist after exposures have been addressed, the focus shifts toward supporting nervous system stabilization and physiologic regulation.

New Leaf Neuro 
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New Leaf Neuro is incorporated in British Columbia, Canada.

Professional Disclosure: 

New Leaf Neuro

New Leaf Neuro provides environmental health education, environmental report interpretation, and wellness consulting services in British Columbia.

We are not a medical clinic and do not employ practitioners licensed under the Health Professions and Occupations Act (HPOA). Our services are educational and informational in nature and do not constitute medical diagnosis, treatment, or the performance of restricted activities under provincial healthcare regulations.

Environmental guidance and report interpretations are based on client-provided information and third-party environmental testing. These services are educational and are not a substitute for professional environmental inspection, remediation services, or building assessment.

Individuals experiencing health concerns should consult a regulated healthcare professional for medical advice regarding  health conditions.

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